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ChromaDex mitraphylline 1
Figure 2. HPLC-PDA monitoring of alkaloid isomerization after heating under reflux of pentacyclic oxindole alkaloid (POA) (a) and tetracyclic oxindole alka loids (TOA) (b) in dynamic maceration (DM) extract; Comparison of interconversion between mitraphylline (1) and isomitraphylline (2) in DM extract (c) and reference solution (d); Black line and gray line for POA with cis and trans D/E ring junction, respectively. Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6) rhyncophylline (7), and isorhyncophylline (8)
Mitraphylline 1, supplied by ChromaDex, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
mitraphylline 1 - by Bioz Stars, 2026-04
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1) Product Images from "Cat's claw oxindole alkaloid isomerization induced by common extraction methods"

Article Title: Cat's claw oxindole alkaloid isomerization induced by common extraction methods

Journal: Química Nova

doi: 10.1590/s0100-40422013000600012

Figure 2. HPLC-PDA monitoring of alkaloid isomerization after heating under reflux of pentacyclic oxindole alkaloid (POA) (a) and tetracyclic oxindole alka loids (TOA) (b) in dynamic maceration (DM) extract; Comparison of interconversion between mitraphylline (1) and isomitraphylline (2) in DM extract (c) and reference solution (d); Black line and gray line for POA with cis and trans D/E ring junction, respectively. Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6) rhyncophylline (7), and isorhyncophylline (8)
Figure Legend Snippet: Figure 2. HPLC-PDA monitoring of alkaloid isomerization after heating under reflux of pentacyclic oxindole alkaloid (POA) (a) and tetracyclic oxindole alka loids (TOA) (b) in dynamic maceration (DM) extract; Comparison of interconversion between mitraphylline (1) and isomitraphylline (2) in DM extract (c) and reference solution (d); Black line and gray line for POA with cis and trans D/E ring junction, respectively. Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6) rhyncophylline (7), and isorhyncophylline (8)

Techniques Used: Reflux, Comparison

Figure 3. The first derivative (dx/dy) from the data fitted by Weibull equation in function of reaction time of pentacyclic oxindole alkaloid (POA) having cis D/E (a) and trans D/E ring junctions (b), and tetracyclic oxindole alkaloids (TOA) (c). Mitraphylline (1), isomitraphylline (2), speciophylline (3), ptero podine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)
Figure Legend Snippet: Figure 3. The first derivative (dx/dy) from the data fitted by Weibull equation in function of reaction time of pentacyclic oxindole alkaloid (POA) having cis D/E (a) and trans D/E ring junctions (b), and tetracyclic oxindole alkaloids (TOA) (c). Mitraphylline (1), isomitraphylline (2), speciophylline (3), ptero podine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)

Techniques Used:

Figure 1S. HPLC-PDA profile of oxindole alkaloids in DM extract, at 245 nm (a); HPLC-MS/MS profiles monitoring the pseudomolecular ions [M+H]+ at m/z 369.3 for pentacyclic oxindole alkaloid (POA), and m/z 385.4 for tetracyclic oxindole alkaloids (TOA) (b); Distinctive transitions of POA at m/z 369.3 → 337.1 (c), and TOA at m/z 385.4 → 353.4 (d); MS/MS spectra of POA (e), and TOA (f). Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)
Figure Legend Snippet: Figure 1S. HPLC-PDA profile of oxindole alkaloids in DM extract, at 245 nm (a); HPLC-MS/MS profiles monitoring the pseudomolecular ions [M+H]+ at m/z 369.3 for pentacyclic oxindole alkaloid (POA), and m/z 385.4 for tetracyclic oxindole alkaloids (TOA) (b); Distinctive transitions of POA at m/z 369.3 → 337.1 (c), and TOA at m/z 385.4 → 353.4 (d); MS/MS spectra of POA (e), and TOA (f). Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)

Techniques Used: Tandem Mass Spectroscopy



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ChromaDex mitraphylline 1
Figure 2. HPLC-PDA monitoring of alkaloid isomerization after heating under reflux of pentacyclic oxindole alkaloid (POA) (a) and tetracyclic oxindole alka loids (TOA) (b) in dynamic maceration (DM) extract; Comparison of interconversion between mitraphylline (1) and isomitraphylline (2) in DM extract (c) and reference solution (d); Black line and gray line for POA with cis and trans D/E ring junction, respectively. Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6) rhyncophylline (7), and isorhyncophylline (8)
Mitraphylline 1, supplied by ChromaDex, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mitraphylline 1/product/ChromaDex
Average 86 stars, based on 1 article reviews
mitraphylline 1 - by Bioz Stars, 2026-04
86/100 stars
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Figure 2. HPLC-PDA monitoring of alkaloid isomerization after heating under reflux of pentacyclic oxindole alkaloid (POA) (a) and tetracyclic oxindole alka loids (TOA) (b) in dynamic maceration (DM) extract; Comparison of interconversion between mitraphylline (1) and isomitraphylline (2) in DM extract (c) and reference solution (d); Black line and gray line for POA with cis and trans D/E ring junction, respectively. Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6) rhyncophylline (7), and isorhyncophylline (8)

Journal: Química Nova

Article Title: Cat's claw oxindole alkaloid isomerization induced by common extraction methods

doi: 10.1590/s0100-40422013000600012

Figure Lengend Snippet: Figure 2. HPLC-PDA monitoring of alkaloid isomerization after heating under reflux of pentacyclic oxindole alkaloid (POA) (a) and tetracyclic oxindole alka loids (TOA) (b) in dynamic maceration (DM) extract; Comparison of interconversion between mitraphylline (1) and isomitraphylline (2) in DM extract (c) and reference solution (d); Black line and gray line for POA with cis and trans D/E ring junction, respectively. Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6) rhyncophylline (7), and isorhyncophylline (8)

Article Snippet: The mitraphylline (1) (Phytolab, batch 2946, Germany) and isomitraphylline (2) (Chromadex, batch 09417-101, USA) were used as external standards.

Techniques: Reflux, Comparison

Figure 3. The first derivative (dx/dy) from the data fitted by Weibull equation in function of reaction time of pentacyclic oxindole alkaloid (POA) having cis D/E (a) and trans D/E ring junctions (b), and tetracyclic oxindole alkaloids (TOA) (c). Mitraphylline (1), isomitraphylline (2), speciophylline (3), ptero podine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)

Journal: Química Nova

Article Title: Cat's claw oxindole alkaloid isomerization induced by common extraction methods

doi: 10.1590/s0100-40422013000600012

Figure Lengend Snippet: Figure 3. The first derivative (dx/dy) from the data fitted by Weibull equation in function of reaction time of pentacyclic oxindole alkaloid (POA) having cis D/E (a) and trans D/E ring junctions (b), and tetracyclic oxindole alkaloids (TOA) (c). Mitraphylline (1), isomitraphylline (2), speciophylline (3), ptero podine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)

Article Snippet: The mitraphylline (1) (Phytolab, batch 2946, Germany) and isomitraphylline (2) (Chromadex, batch 09417-101, USA) were used as external standards.

Techniques:

Figure 1S. HPLC-PDA profile of oxindole alkaloids in DM extract, at 245 nm (a); HPLC-MS/MS profiles monitoring the pseudomolecular ions [M+H]+ at m/z 369.3 for pentacyclic oxindole alkaloid (POA), and m/z 385.4 for tetracyclic oxindole alkaloids (TOA) (b); Distinctive transitions of POA at m/z 369.3 → 337.1 (c), and TOA at m/z 385.4 → 353.4 (d); MS/MS spectra of POA (e), and TOA (f). Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)

Journal: Química Nova

Article Title: Cat's claw oxindole alkaloid isomerization induced by common extraction methods

doi: 10.1590/s0100-40422013000600012

Figure Lengend Snippet: Figure 1S. HPLC-PDA profile of oxindole alkaloids in DM extract, at 245 nm (a); HPLC-MS/MS profiles monitoring the pseudomolecular ions [M+H]+ at m/z 369.3 for pentacyclic oxindole alkaloid (POA), and m/z 385.4 for tetracyclic oxindole alkaloids (TOA) (b); Distinctive transitions of POA at m/z 369.3 → 337.1 (c), and TOA at m/z 385.4 → 353.4 (d); MS/MS spectra of POA (e), and TOA (f). Mitraphylline (1), isomitraphylline (2), speciophylline (3), uncarine F (4), pteropodine (5), isopteropodine (6), rhyncophylline (7), and isorhyncophylline (8)

Article Snippet: The mitraphylline (1) (Phytolab, batch 2946, Germany) and isomitraphylline (2) (Chromadex, batch 09417-101, USA) were used as external standards.

Techniques: Tandem Mass Spectroscopy